Amphotericin B has been the standard treatment for systemic yeast infections for 40 years. Amphotericin B is a polyene with a high rate of success in managing oral candidiasis.
It inhibits the activity of Candida and other fungus by attaching to ergosterol, the primary sterol associated with the fungal cell membrane.
By disrupting the fungal cell membrane’s osmotic integrity, amphotericin B causes leakage of biochemical components such as potassium, magnesium and metabolites, and causes cell death. However, due to problems with toxicity of amphotericin B, azole antifungal compounds have become more popular in recent years.
Azoles are less toxic. They inhibit synthesis of ergosterol by affecting the cytochrome P-450 enzyme which is responsible for 14-alpha-demethylation. While having lower toxicity, azoles only exhibit fungistatic properties. That is to say, these compounds will only inhibit the growth and reproduction of fungi, but will not destroy them completely.
One of the most important things in using azole compounds to treat a vaginal yeast infection is ensuring that you actually have a vaginal infection of Candida albicans rather than a bacterial infection. You may wish to get advice from your doctor.
One of the big issues around azole treatment in recent years has been the development of Candida albicans’ resistance to azole medication, with strains emerging which show no response to treatment.
Obviously this could potentially become a big problem in years to come, rather like antibiotic resistance, so it’s important that you actually know you have a yeast infection before you begin treatment.
Having said that, vaginal yeast infections can indeed recur over time, so if the same symptoms occur again and again, self treating with azole medicines that are available as over-the-counter products is recommended. But do you see the problem here?
Just as Linda Allen says in Yeast Infection No More, the recurrence of symptoms is a clear sign that something is out of balance in your body – and whatever that is, it is allowing yeast infections to recur over and over again. Treating them with medications that are potentially toxic and have side-effects is at best a compromise.
So what I recommend at this stage is that if you’re having repeated vaginal infections you certainly may choose to use azole medications to deal with the problem on a short-term basis.
Longer-term it would be well worthwhile looking at the recommendations and strategies laid out in yeast infection no more, because these are truly holistic and will give you a long-term relief from yeast infections.
Assuming you wish to use vaginal antifungal agents for short-term relief, you can choose between over-the-counter products in various forms: ointment, cream, suppository, tablet, and even tampons.
But if you’ve had allergic reactions to any medication in the past, or allergic reactions to medications in this category, it’s essential that you tell your health care provider about it before you start taking them!
Also, if you have had any reaction to food dyes, preservatives or other environmental substances, this needs to be reported to a doctor or health care professional for your own safety. So with such health risks, you might be thinking even now that you could benefit from a holistic program like yeast Infection No More!
Furthermore, we do know that azoles are not recommended for use during pregnancy, because they’ve not been thoroughly tested; also the hormonal changes that are associated with pregnancy could render them ineffective, so again it’s worth talking to a doctor.
And finally, if you are taking warfarin, then you certainly should not be using these medications as there is a significant interaction between azoles and warfarin.
Depending on the product you buy, you may simply have to take a tablet, or you may need to take a tablet/suppository combination. Furthermore, there may be a cream that can be applied on the vulva to stop itching. These combo treatments are called combination packs.
To clear up your infection completely, you must use the medication for the full-length of treatment recommended, even if the symptoms begin to disappear shortly after treatment has commenced. The simple fact is this: if you give up using it too soon your symptoms may return. With yeast infection no more, the claim made in the yeast infection no more e-Book for these morish home remedies is that the cure is permanent.
Azoles are not actually agents that destroy fungi like Candida completely; they simply limit its growth, so if you give it a chance to return by ceasing treatment too soon it will come back. That’s where a complete holistic home remedy for yeast infection comes out on top!
It also follows, I think you’ll probably agree, that if you have some kind of imbalance in your body in the first place, an imbalance that is allowing the Candida albicans to overgrow, treating it with azoles will not provide a complete solution.
It will only provide temporary relief. So that is why the holistic approach described in Yeast Infection No More is more worthwhile than you might expect.
Home remedies for yeast infections have been around for generations, and in general they are based on sound scientific principles, even if science hasn’t yet got around to demonstrating that fact!
In the case of infection with Candida albicans, a holistic approach will allow you to re-establish a bodily environment in which yeast can’t flourish. If you’re suffering repeated yeast infections it must surely be obvious that the reason this is happening is that there is something fundamentally wrong with your body chemistry. (Too much sugar, too many drugs, too much stress, too much alcohol…..you name it.)
When the body chemistry is in perfect balance, yeast infections don’t show up because they’re held in check by the probiotic bacteria in the vagina and on the skin that naturally limit the growth of Candida organisms.
For this reason alone I highly recommend you check out Yeast Infection No More. You can find a link to it on the right-hand side of this page.
Having said that I agree that you may want to take the azole route for relief from the intense itching that yeast infections can produce.
The dose of azole that is appropriate for different individuals is variable, so your doctor will probably have advised you how much to take, and how often.
If you’ve bought an over-the-counter preparation, then the patient information leaflet that is enclosed with the product should give you directions on how much to take. You can get full information about this aspect of azole medication here.
If your symptoms have not actually improved within three days of beginning the medication, or have not entirely disappeared within a week, you should check with your doctor to see what’s happening.
One of the reasons for this is that not all vaginal infections are caused by yeast, some are bacterial. Furthermore, if symptoms recur within two months you should go back and see your doctor.
Other simple precautions – in a way, the simplest kind of home remedies – that can help you clear up a vaginal yeast infection include the use of cotton underwear rather than synthetic. Also you should ensure that you are wearing clean underwear and maintaining good personal hygiene at all times.
It’s been said that vaginal yeast infections are not transmitted by having sex, so a sexual partner doesn’t need to be treated for the infection.
I’d question the suggestion that yeast infections are not transmissible between sexual partners: in my opinion if one partner has a yeast infection, whether it’s the woman or man (you can read more about male yeast infections here) then you should be practicing safe sex until the infection has cleared up. Safe sex means using a condom to prevent cross infection.
Regrettably the Catch-22 with that suggestion is that azole medications often contain oils that can weaken a latex condom and increase the chances of the condom breaking when you’re making love.
Side-effects of azole medication include vaginal burning, some kind of discharge, or other irritation. It’s rare to experience these, or the more serious side-effects such as skin rash, but they do occur from time to time, and if this happens to you, you need to see your healthcare professional immediately.
Once again, you can read the leaflet that comes with the product to establish the risks and the possible rewards: please bear in mind that these medications may not be a permanent cure, and you may need to use a holistic solution to re-establish the correct chemical balance in your body that is going to prevent Candida albicans flourishing.